Ppt hexose monophosphate shunt powerpoint presentation. Hexose monophosphate shunt an overview sciencedirect. Evaluation of adenosine 5 monophosphate and fluoride as adenylate kinase inhibitors in the creatine kinase assay. While the sequence of glycolysis, pdh and tca cycle involves both the cytosol and the mitochondria, the hms runs entirely in the cytosol. What is the pentose phosphate pathway and its significance. Pentose phosphate pathway ppp n hexose monophosphate pathway shunt n active in certain tissues e. The hmp shunt is an alternative pathway to glycolysis and is used to produce. The hexose monophosphate pathway is used for the production of nadph from nadp the nadph is required for biosynthetic reactions such as fatty acid synthesis, cholesterol synthesis, drug reduction, and as a cofactor for some nonsynthetic enzymatic reactions. The hexose monophosphate shunt, also known as the pentose. Pentose phosphate pathway hexose monophosphate shunt to understand the function of the pentose phosphate pathway in production of.
Read and learn for free about the following article. Pentose phosphate pathway hexose monophosphate shunt objectives to understand the function of the pentose phosphate pathway in production of nadph and ribose precursors for nucleic acid. Pentose phosphate pathway hexose monophosphate shunt overview oxidative branch of glucose nonoxidative. Pentose phosphate pathway hexose monophosphate shunt gmch. Nadph which is generated in the oxidative branch of the pathway can feed back and inhibit the pathway. Biochemistry, hexose monophosphate pathway statpearls ncbi. Hexose monophosphate pathway or pentose phosphate pathway. One of these alternate pathway is the pentose phosphate pathway or also called as hexose monophosphate pathway in which oxidation of glucose 6phosphate takes place to produce pentoses. Metabolism lecture 5 pentose phosphate pathway restricted for students enrolled in mcb102, uc berkeley, spring 2008 only regulation of the pentose phosphate pathway. Regeneration modes red blood cells glucose 6p dehydrogenase deficency white blood cells. The pentose phosphate pathway ppp also called hexose monophosphate shunt, hms. Although deficiencies of a number of rbc enzymes in the glycolytic and hexose monophosphate pathways may result in hemolytic anemia, the only one that is discussed here is the most common one, glucose6phosphate dehydrogenase g6pd deficiency.
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